10-Hydroxy Camptothecin

• Catalog No.: H875000
• CAS Number: 19685-09-7
• M. F.: C20H16N2O5
• M. W.: 364.35144
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
• IUPAC Traditional name: (19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
• Synonyms: (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC 107124; Hydroxycamptothecin; (S)-10-Hydroxycamptothecin

DATABASE IDS

• CAS Number: 19685-09-7

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: >250°C (dec.)
• Solubility: Dimethylformamide
• Solubility: Dimethyl Sulfoxide
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A Camptothecin derivative; a topoisomerase inhibitor for cancer therapy.

REFERENCES

• Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986)
• Miller, K.D., et al.: Invest. New Drugs, 22, 69 (1986)
• Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (1986)
• Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (1986)