Home > Compound List > Product Information
rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride_Molecular_structure_CAS_81408-49-3)
Click picture or here to close

rac erythro-9-(2-Hydroxy-3-nonyl)adenine, Hydrochloride

Catalog No. H825550 Name Toronto Research Chemicals
CAS Number 81408-49-3 Website http://www.trc-canada.com
M. F. C14H24ClN5O Telephone +1 (416) 665-9696
M. W. 313.82626 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere Chembase ID: 170232

SYNONYMS

IUPAC name
(2R,3S)-3-(6-amino-9H-purin-9-yl)nonan-2-ol hydrochloride
IUPAC Traditional name
(2R,3S)-3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride
Synonyms
EHNA

DATABASE IDS

CAS Number 81408-49-3

PROPERTIES

Certificate of Analysis Download
Apperance White to Off-White Solid
Melting Point 163-170°C
Solubility DMSO
Solubility Water
MSDS Link Download
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
A potent inhibitor of phosphodiesterase II (PDE II) (IC50=800nM). Does ot inhibit other PDE isozymes (IC50>100uM). Inhibits the retrograde transport motor, dynein. Also inhibits adenosine deaminase (Ki=4nM).

REFERENCES

  • Lorbar, M., et al.: J. Mol. Cell. Cardiol., 31, 401 (1999)
  • Verde, I., et al.: Br. J. Pharmacol., 127, 65 (1999)