rac cis-3-Hydroxy Apatinib 3-O-β-D-Glucuronide

• Catalog No.: H802110
• CAS Number: 1376331-61-1
• M. F.: C30H31N5O8
• M. W.: 589.59584

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6R)-6-{[(1R)-3-cyano-3-(4-{2-[(pyridin-4-ylmethyl)amino]pyridine-3-amido}phenyl)cyclopentyl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6R)-6-{[(1R)-3-cyano-3-(4-{2-[(pyridin-4-ylmethyl)amino]pyridine-3-amido}phenyl)cyclopentyl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: cis-3-Hydroxyapatinib β-O-Glucuronide; rel-(1R,3R)]-3-Cyano-3-[4-[[[2-[(4-pyridinylmethyl)amino]-3-pyridinyl]carbonyl]amino]phenyl]cyclopentyl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 1376331-61-1

DETAILS

Description (English)

cis-3-Hydroxy Apatinib 3-O-β-D-Glucuronide is a glucuronide conjugate of cis-3-Hydroxy Apatinib and a metabolite of the antiangiogenic agent and selective VEGFR2 inhibitor Apatinib (A726150).

REFERENCES

• Ding, J, et al.: J. Chrom B Anal. Technol. Biomed. Life Sci., 895, 108 (2012)