7-Hydroxy Aminopterin

• Catalog No.: H797250
• CAS Number: 97772-99-1
• M. F.: C19H20N8O6
• M. W.: 456.4121
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2S)-2-[(4-{[(2,4-diamino-7-hydroxypteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
• IUPAC Traditional name: (2S)-2-[(4-{[(2,4-diamino-7-hydroxypteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
• Synonyms: N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; N-[4-[[(2,4-Diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl]amino]benzoyl]- L-Glutamic Acid; N-[p-[[(2,4-Diamino-7-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid

DATABASE IDS

• CAS Number: 97772-99-1

PROPERTIES

• Apperance: Red Solid
• Melting Point: >165°C (dec.)
• Solubility: Water
• Storage Condition: Refrigerator

DETAILS

Description (English)

The 7-hydroxy metabolite of Aminopterin (A628850) as substrate for folylpolyglutamate synthetase (FPGS).

REFERENCES

• Schoo, M.M.J., et al.: Cancer Res., 45, 3034 (1985)