HX 630-d4

• Catalog No.: H674252
• M. F.: C28H27NO2S
• M. W.: 441.58448

SYNONYMS

• IUPAC name: 4-{14,14,17,17-tetramethyl-2-thia-9-azatetracyclo[9.8.0.0^3,^8.0^1^3,^1^8]nonadeca-1(19),3(8),4,6,9,11,13(18)-heptaen-10-yl}(^2H₄)benzoic acid
• IUPAC Traditional name: 4-{14,14,17,17-tetramethyl-2-thia-9-azatetracyclo[9.8.0.0^3,^8.0^1^3,^1^8]nonadeca-1(19),3(8),4,6,9,11,13(18)-heptaen-10-yl}(^2H₄)benzoic acid
• Synonyms: 4-(7,8,9,10-tetrahydro-7,7,10,10-tetramethylbenzo[b]naphtho[2,3-f][1,4]thiazepin-12-yl)benzoic Acid-d4

DETAILS

Description (English)

The labelled analogue of a nuclear receptor retinoid X receptor (RXR) agonist that exerts antiproliferative effects in vascular smooth muscle cells (VSMCs) in vivo and in vitro. A potential therapeutic target for vascular injury and intimal thickening. It

REFERENCES

• Haraguchi, G. et al.: J. Mol. Cell. Cardiol., 41, 885 (2006)
• Nishimaki-M. et al.: Biochem. Pharmacol., 76, 1006 (2006)