HU 308

• Catalog No.: H673525
• CAS Number: 256934-39-1
• M. F.: C27H42O3
• M. W.: 414.62058

SYNONYMS

• IUPAC name: [(1S,4S,5S)-4-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methanol
• IUPAC Traditional name: [(1S,4S,5S)-4-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methanol
• Synonyms: (1R,4R,5R)-rel-(+)-4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol

DATABASE IDS

• CAS Number: 256934-39-1

DETAILS

Description (English)

A specific CB2-specific agonist that inhibits forskolin-stimulated cAMP production in CB2-transfected cells. It reduces blood pressure, blocks defecation, and elicits anti-inflammatory and peripheral analgesic activity and thus may lead to new therapies f

REFERENCES

• Hanus, L. et al.: Proc. Nat. Acad. Sci. USA, 96, 14228 (1999)
• Labud, C.J. et al.: Eur. J. Pharmacol., 527, 172 (1999)
• Martin-Moreno, A.M. et al.: Molec. Pharmacol., 79, 964 (1999)