HT-2 Toxin

• Catalog No.: H671800
• CAS Number: 26934-87-2
• M. F.: C22H32O8
• M. W.: 424.48468

SYNONYMS

• IUPAC name: (1'S,2S,2'R,4'S,7'R,9'R,10'R,11'S)-2'-[(acetyloxy)methyl]-10',11'-dihydroxy-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0^2,^7]dodecan]-5'-en-4'-yl 3-methylbutanoate
• IUPAC Traditional name: (1'S,2S,2'R,4'S,7'R,9'R,10'R,11'S)-2'-[(acetyloxy)methyl]-10',11'-dihydroxy-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0^2,^7]dodecan]-5'-en-4'-yl 3-methylbutanoate
• Synonyms: Isovaleric Acid 8-Ester with 12,13-epoxytrichothec-9-ene-3α,4β,8α,15-tetrol 15-Acetate; 3,4-Dihydroxy-15-acetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-Δ9-trichothecene; NSC 278571; HT 2; Mycotoxin HT 2; (3α,4β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 8-(3-Methylbutanoate) 15-Acetate; 12,13-Epoxytrichothec-9-ene-3α,4β,8α,15-tetro 15-Acetate 8-Isovalerate; HT 2 Toxin; Toxin HT 2

DATABASE IDS

• CAS Number: 26934-87-2

DETAILS

Description (English)

HT-2 Toxin is a trichothecene group mycotoxin. HT-2 Toxin is the 4-hydroxy analogue of T-2 Toxin (T002980) which has been shown to induce DNA damage and cell death on prolonged administration.

REFERENCES

• Weidner, M. et al.: J. Agric. Food Chem., 60, 5676 (2012)
• Choi, H. et al.: Toxicol. Appl. Pharmacol., 240, 46 (2012)
• Amuzie, C. et al.: Toxicol. Sci., 113, 412 (2012)