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Hexyl Methanethiosulfonate_Molecular_structure_CAS_53603-16-0)
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Hexyl Methanethiosulfonate

Catalog No. H297150 Name Toronto Research Chemicals
CAS Number 53603-16-0 Website http://www.trc-canada.com
M. F. C7H16O2S2 Telephone +1 (416) 665-9696
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Storage Refrigerator, Under Inert Atmosphere Chembase ID: 169982

SYNONYMS

IUPAC name
1-(methanesulfonylsulfanyl)hexane
IUPAC Traditional name
1-(methanesulfonylsulfanyl)hexane
Synonyms
HMTS
Methanesulfonothioic Acid S-Hexyl Ester

DATABASE IDS

CAS Number 53603-16-0

PROPERTIES

Certificate of Analysis Download
Apperance Light Yellow Oil
Solubility Chloroform
Solubility Ethanol
MSDS Link Download
Storage Condition Refrigerator, Under Inert Atmosphere
Storage Warning Store Under Inert Atmosphere

DETAILS

Description (English)
Reacts specifically and rapidly with thiols to form mixed disulfides. PMTS covalently binds to cystein residues introduced into a specific second transmembrane site in the glycine receptor and g-aminobutyric acid type A receptor subunits and irreversibly

REFERENCES

  • Xu, M. & Akabus, M.H.: J. Biol. Chem., 268, 21505 (1993)
  • Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993)
  • Yang, N. et al.: Neuron, 16, 113 (1993)
  • Kuner, T. et al.: Neuron, 17, 343 (1993)
  • Mascia, M.P., et al.: PNAS, 97, 16, 9305 (2000)