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(3S,4S)-3-Hexyl-4-[(2R)-2-hydroxytridecyl]-2-oxetanone_Molecular_structure_CAS_104872-06-2)
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(3S,4S)-3-Hexyl-4-[(2R)-2-hydroxytridecyl]-2-oxetanone

Catalog No. H296530 Name Toronto Research Chemicals
CAS Number 104872-06-2 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
(3S)-3-hexyl-4-[(2R)-2-hydroxytridecyl]oxetan-2-one
IUPAC Traditional name
(3S)-3-hexyl-4-[(2R)-2-hydroxytridecyl]oxetan-2-one
Synonyms
[3S-[3α,4β(S*)]]-3-Hexyl-4-(2-hydroxytridecyl)-2-oxetanone

DATABASE IDS

CAS Number 104872-06-2

PROPERTIES

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DETAILS

Description (English)
(3S,4S)-3-Hexyl-4-[(2R)-2-hydroxytridecyl]-2-oxetanone is an analog of Tetrahydrolipstatin, an inhibitor of the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG), also an intermediate in the preparation of Orlistat (O686500).

REFERENCES

  • Di Marzo, V., et al.: Nat. Rev. Drug Discovery, 7, 438 (1995)
  • Ortar, G., et al.: J. Med. Chem., 51, 6970 (1995)
  • Mechoulam, R., et al.: Biochem. Pharmacol., 50, 83 (1995)
  • Bisogno, T., et al.: J. Cell Biol., 163, 463 (1995)