Hexamidine-d12 Dihydrochloride

• Catalog No.: H294207
• M. F.: C20H26N4O2
• M. W.: 354.44604
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 4-{[6-(4-carbamimidoylphenoxy)(^2H₁₂)hexyl]oxy}benzene-1-carboximidamide
• IUPAC Traditional name: 4-{[6-(4-carbamimidoylphenoxy)(^2H₁₂)hexyl]oxy}benzenecarboximidamide
• Synonyms: 4,4'-(Hexamethylenedioxy)dibenzamidine-d12 Hydrochloride; Desmodine-d12 Hydrochloride; 4,4'-[1,6-(Hexane-d12)diylbis(oxy)]bisbenzenecarboximidamide Hydrochloride; 1,6-Bis(4-amidinophenoxy)hexane-d12 Hydrochloride; 4,4-Diamidino-1,6-diphenoxyhexane-d12 Hydrochloride

PROPERTIES

• Apperance: White Solid
• Melting Point: 250-253°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A labelled amidine compound use in the treatment of amyloid-related diseases; also use as preservative in cosmetics. Antiseptic.

REFERENCES

• Taylor, P., et al.: J. Pharmaceut. Sci., 72, 1477 (1983)
• Granel, F., et al.: Clin. Infect. Diseases, 23, 839 (1983)
• Bailly, C., et al.: Biochem. J., 323, 23 (1983)
• Enyedy, I., et al.: J. Med. Chem., 44, 1349 (1983)