Homopravastatin Lactone Di-(tert-butyldimethylsilyl) Ether

• Catalog No.: H602910
• CAS Number: 159224-68-7
• M. F.: C36H64O6Si2
• M. W.: 649.06076

SYNONYMS

• IUPAC name: (1S,3S,7S,8S,8aR)-3-[(tert-butyldimethylsilyl)oxy]-8-{2-[(2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylpentanoate
• IUPAC Traditional name: (1S,3S,7S,8S,8aR)-3-[(tert-butyldimethylsilyl)oxy]-8-{2-[(2R,4R)-4-[(tert-butyldimethylsilyl)oxy]-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylpentanoate
• Synonyms: 2-Methyl-pentanoic Acid [1S-[1α(R*),3β,7β,8β(2S*,4S*),8aβ]]-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-8-[2-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-7-methyl-1-naphthalenyl Ester

DATABASE IDS

• CAS Number: 159224-68-7

PROPERTIES

• Apperance: Yellow Oil
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate

DETAILS

Description (English)

Homopravastatin (H603000) derivative, an impurity of Pravastatin (P702000).

REFERENCES

• O'Connor, P., et al.: Br. Med. J., 300, 667 (1990)
• Vickers, S., et al.: Drug. Metab. Dispos., 18, 138 (1990)
• Ellison, D., et al.: Anal. Profiles Drug Subst. Excipients, 22, 359 (1990)
• Reddy, K., et al.: J. Pharm. Biomed. Anal., 32, 461(1990)