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H-1152 Glycyl Dihydrochloride_Molecular_structure_CAS_913844-45-8)
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H-1152 Glycyl Dihydrochloride

Catalog No. H011530 Name Toronto Research Chemicals
CAS Number 913844-45-8 Website http://www.trc-canada.com
M. F. C18H24N4O3S Telephone +1 (416) 665-9696
M. W. 376.47316 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 169821

SYNONYMS

IUPAC name
2-amino-1-[(3S)-3-methyl-4-[(4-methylisoquinolin-5-yl)sulfonyl]-1,4-diazepan-1-yl]ethan-1-one
IUPAC Traditional name
2-amino-1-[(3S)-3-methyl-4-(4-methylisoquinolin-5-ylsulfonyl)-1,4-diazepan-1-yl]ethanone
Synonyms
2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride
(2S)-4-(Aminoacetyl)hexahydro-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride

DATABASE IDS

CAS Number 913844-45-8

PROPERTIES

Certificate of Analysis Download
Apperance Pale-Yellow Solid
Melting Point 190-192°C
Solubility DMSO
Solubility Methanol
Solubility Water
MSDS Link Download
Storage Condition Refrigerator
Storage Warning Hygroscopic

DETAILS

Description (English)
A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis.

REFERENCES

  • Tamura, M., et al.: Biochim. Biophys. Acta, 1754, 245 (2005)