H-1152 Glycyl Dihydrochloride_Molecular_structure_CAS_913844-45-8)

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H-1152 Glycyl Dihydrochloride
Catalog No.	H011530	Name	Toronto Research Chemicals
CAS Number	913844-45-8	Website	http://www.trc-canada.com
M. F.	C18H24N4O3S	Telephone	+1 (416) 665-9696
M. W.	376.47316	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage	Refrigerator	Chembase ID: 169821

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SYNONYMS

IUPAC name

2-amino-1-[(3S)-3-methyl-4-[(4-methylisoquinolin-5-yl)sulfonyl]-1,4-diazepan-1-yl]ethan-1-one

IUPAC Traditional name

2-amino-1-[(3S)-3-methyl-4-(4-methylisoquinolin-5-ylsulfonyl)-1,4-diazepan-1-yl]ethanone

Synonyms

2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride

(2S)-4-(Aminoacetyl)hexahydro-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride

DATABASE IDS

CAS Number

913844-45-8

PROPERTIES

Certificate of Analysis	Download
Apperance	Pale-Yellow Solid
Melting Point	190-192°C
Solubility	DMSO
Solubility	Methanol
Solubility	Water
MSDS Link	Download
Storage Condition	Refrigerator
Storage Warning	Hygroscopic

DETAILS

Description (English)

A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis.

REFERENCES

Tamura, M., et al.: Biochim. Biophys. Acta, 1754, 245 (2005)