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S-[2-(N7-Guanyl)ethyl]glutathione_Molecular_structure_CAS_100840-34-4)
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S-[2-(N7-Guanyl)ethyl]glutathione

Catalog No. G843800 Name Toronto Research Chemicals
CAS Number 100840-34-4 Website http://www.trc-canada.com
M. F. C17H24N8O7S Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
(2S)-2-amino-4-{[(1R)-2-{[2-(2-amino-6-oxo-6,7-dihydro-3H-purin-7-yl)ethyl]sulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid
IUPAC Traditional name
(2S)-2-amino-4-{[(1R)-2-{[2-(2-amino-6-oxo-3H-purin-7-yl)ethyl]sulfanyl}-1-(carboxymethylcarbamoyl)ethyl]carbamoyl}butanoic acid
Synonyms
N-[S-[2-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)ethyl]-N-L-γ-glutamyl-L-cysteinyl]glycine
L-γ-Glutamyl-S-[2-(2-amino-1,6-dihydro-6-oxo-7H-purin-7-yl)ethyl]-L-cysteinylglycine
S-[2-(N7-guanyl)ethyl]GSH

DATABASE IDS

CAS Number 100840-34-4

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
S-[2-(N7-Guanyl)ethyl]glutathione is a known DNA adduct formed as a result of glutathione (GSH)-dependent base-substitution mutations caused by the carcinogen ethylene dibromide (EDB).

REFERENCES

  • Kim, M.-S. et al.: Che, Res. Toxicol., 11, 311 (1998)
  • Ross, M.K. et al.: Chem.-Biol. Inter., 146, 39 (1998)
  • Ballering, L.A.P. et al.: Mutagenesis, 13, 61 (1998)