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GSK 2126458

Catalog No. G797500 Name Toronto Research Chemicals
CAS Number 1086062-66-9 Website http://www.trc-canada.com
M. F. C25H17F2N5O3S Telephone +1 (416) 665-9696
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Storage Chembase ID: 73048

SYNONYMS

IUPAC name
2,4-difluoro-N-{2-methoxy-5-[4-(pyridazin-4-yl)quinolin-6-yl]pyridin-3-yl}benzene-1-sulfonamide
IUPAC Traditional name
2,4-difluoro-N-{2-methoxy-5-[4-(pyridazin-4-yl)quinolin-6-yl]pyridin-3-yl}benzenesulfonamide
Synonyms
2,4-Difluoro-N-[2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide

DATABASE IDS

CAS Number 1086062-66-9

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
A highly potent inhibitor of PI3K and the mammalian target of Rapamycin.

REFERENCES

  • Samuels, Y., et al.: Science, 304, 554 (2004)
  • Karakas, B., et al.: Br. J. Cancer, 94, 455 (2004)
  • Folkes, A., et al.: J. Med. Chem., 51, 5522 (2004)