Glycochenodeoxycholic Acid-d5 Sodium Salt

• Catalog No.: G641257
• M. F.: C26H42NNaO5
• M. W.: 471.60515

SYNONYMS

• IUPAC name: sodium 2-[(4R)-4-[(1S,2S,5R,7R,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]acetate
• IUPAC Traditional name: sodium 2-[(4R)-4-[(1S,2S,5R,7R,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]acetate
• Synonyms: N-[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine-d5 Sodium Salt; Sodium Glycochenodeoxycholate-d5; NSC 681056-d5 Sodium Chenodeoxycholylglycine-d5; N-[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine-d5 Monosodium Salt; Sodium Glycochenodesoxycholate-d5

DETAILS

Description (English)

Labelled Glycochenodeoxycholic Acid (G641255). A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleret

REFERENCES

• Ollila, F., et al.: Langmuir, 17, 7107 (2001)
• Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2001)
• Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2001)