4-Glutathionyl Cyclophosphamide

• Catalog No.: G597980
• CAS Number: 77273-67-7
• M. F.: C17H30Cl2N5O8PS
• M. W.: 566.393561

SYNONYMS

• IUPAC name: (2S)-2-amino-4-{[(1R)-2-({2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2λ^5-oxazaphosphinan-4-yl}sulfanyl)-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid
• IUPAC Traditional name: (2S)-2-amino-4-{[(1R)-2-({2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2λ^5-oxazaphosphinan-4-yl}sulfanyl)-1-(carboxymethylcarbamoyl)ethyl]carbamoyl}butanoic acid
• Synonyms: N-[S-[2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin-4-yl]-N-L-γ-glutamyl-L-cysteinyl]glycine; L-γ-Glutamyl-S-[2-[bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl]-L-cysteinylglycine

DATABASE IDS

• CAS Number: 77273-67-7

DETAILS

Description (English)

4-Glutathionyl Cyclophosphamide is the gluthione conjugated metabolite of the chemotherapeutic agent, Cyclophosphamide (C988580).

REFERENCES

• Dirven, H.A. et al.: Cancer Res., 54, 6215 (1994)
• Li, F. et al.: Biochem. Pharmacol., 90, 1063 (1994)