(-)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride

• Catalog No.: H294070
• M. F.: C12H16ClNO2
• M. W.: 241.71394
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (4aS,10bS)-2H,3H,4H,4aH,5H,6H,10bH-naphtho[1,2-b]morpholin-9-ol hydrochloride
• IUPAC Traditional name: (4aS,10bS)-2H,3H,4H,4aH,5H,6H,10bH-naphtho[1,2-b]morpholin-9-ol hydrochloride
• Synonyms: (4aS,10bS)-3,4,4a,5,6,10b-hexahydro-2H-Naphth[1,2-b]-1,4-oxazin-9-ol, Hydrochloride

PROPERTIES

• Apperance: Off-White Powder
• Melting Point: 310-315°C (dec.)
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A dopamine antagonist. A dopaminergic ligand. This compound has been used as a precursor for the PET radiotracer, 11C-(-)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol.

REFERENCES

• Dijkstra, D., et al.: J. Med. Chem., 45, 3022 (2002)
• Wilson, A.A. et al.: J. Med. Chem., 48, 4153 (2005)