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D-Glucoheptono-1,4-lactone_Molecular_structure_CAS_60046-25-5)
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D-Glucoheptono-1,4-lactone

Catalog No. G416500 Name Toronto Research Chemicals
CAS Number 60046-25-5 Website http://www.trc-canada.com
M. F. C7H12O7 Telephone +1 (416) 665-9696
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Storage Chembase ID: 169649

SYNONYMS

IUPAC name
(3S,5S)-3,4-dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]oxolan-2-one
IUPAC Traditional name
(3S,5S)-3,4-dihydroxy-5-[(1R,2R)-1,2,3-trihydroxypropyl]oxolan-2-one
Synonyms
Glucoheptonic Acid γ-Lactone
(2ξ)-D-Glucoheptonic Acid γ-Lactone
D-Glucoheptonolactone

DATABASE IDS

CAS Number 60046-25-5

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
It is used in the synthesis of Howiinol A and its analogs. Howiinol A was one of the active antitumor constituents from the root and stem bark of Goniothamus howii (Annonaceae), and it was synthesized in 9 steps from α-D-glucoheptonic γ-lactone. Twenty-si

REFERENCES

  • Dhanvantari, S., et al.: J. Biol. Chem., 275, 29887 (2000)
  • Kjellin, U., et al.: Langmuir, 17, 1941 (2000)