Gisadenafil Besylate

• Catalog No.: G388700
• CAS Number: 334827-98-4
• M. F.: C29H39N7O8S2
• M. W.: 677.79206

SYNONYMS

• IUPAC name: 5-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]pyridin-3-yl}-3-ethyl-2-(2-methoxyethyl)-2H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one; benzenesulfonic acid
• IUPAC Traditional name: 5-[2-ethoxy-5-(4-ethylpiperazin-1-ylsulfonyl)pyridin-3-yl]-3-ethyl-2-(2-methoxyethyl)-4H-pyrazolo[4,3-d]pyrimidin-7-one; benzenesulfonic acid
• Synonyms: 5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]-3-pyridinyl]-3-ethyl-2,6-dihydro-2-(2-methoxyethyl)-7H-pyrazolo[4,3-d]pyrimidin-7-one Benzenesulfonate; 1-[[6-Ethoxy-5-[3-ethyl-4,7-dihydro-2-(2-methoxyethyl)-7-oxo-2H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-pyridinyl]sulfonyl]-4-ethylpiperazine Monobenzenesulfonate; UK 369003-26

DATABASE IDS

• CAS Number: 334827-98-4

DETAILS

Description (English)

Gisadenafil (UK 369003) is a PDE5 inhibitor. It is 80 fold selective over PDE6, and greater than 3000 fold selective over PDEs 1-4 and 7. Gisadenafil is used for the treatment of LUTS.

REFERENCES

• Bloch, W., et al.: Prostate, 33, 1 (1997)
• Glowienke, S., et al.: Mutat. Res., 581, 23 (1997)
• Chapple, C., et al.: Eur. Urol., 54, 563 (1997)
• Elder, D., et al.: J. Pharm. Pharmacol., 61, 269 (1997)