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Genistein-4,6,2',3',5',6'-d6Discontinued See G350010_Molecular_structure_CAS_)
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Genistein-4,6,2',3',5',6'-d6Discontinued See G350010

Catalog No. G350002 Name Toronto Research Chemicals
CAS Number Website http://www.trc-canada.com
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Storage Chembase ID: 169608

SYNONYMS

IUPAC name
5,7-dihydroxy-3-[4-hydroxy(2H4)phenyl](6,8-2H2)-4H-chromen-4-one
IUPAC Traditional name
5,7-dihydroxy-3-[4-hydroxy(2H4)phenyl](6,8-2H2)chromen-4-one
Synonyms
5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d6
Genisteol-d6
NSC 36586-d6
4',5,7-Trihydroxyisoflavone-d6
GeniVida-d6
Baichanin A-d6
Bonistein-d6
Prunetol-d6
Sophoricol-d6

DATABASE IDS

PROPERTIES

Certificate of Analysis Download
Apperance Light Yellow Solid
MSDS Link Download

DETAILS

Description (English)
Labelled Genistein (G350000). Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of AT

REFERENCES

  • Akiyama, T., et al.: J. Biol. Chem., 262, 5592 (1987)
  • O'Dell, T.J., et al.: Nature, 353, 588 (1987)
  • Aharonovits, O., et al.: Biochim Biophys. Acta, 1112, 181 (1987)
  • Platanias, L.C., et al.: J. Biol. Chem., 267, 24053 (1987)
  • Yoshida, H., et al.: Biochi