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Gemcitabine Monophosphate Formate Salt_Molecular_structure_CAS_116371-67-6)
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Gemcitabine Monophosphate Formate Salt

Catalog No. G305010 Name Toronto Research Chemicals
CAS Number 116371-67-6 Website http://www.trc-canada.com
M. F. C10H14F2N3O9P Telephone +1 (416) 665-9696
M. W. 389.2034274 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere Chembase ID: 169590

SYNONYMS

IUPAC name
formic acid; {[(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid
IUPAC Traditional name
[(2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methoxyphosphonic acid; formic acid
Synonyms
2'-Deoxy-2',2'-difluoro-5'-cytidylic Acid Formate

DATABASE IDS

CAS Number 116371-67-6

PROPERTIES

Certificate of Analysis Download
Apperance White to Off-White Solid
Melting Point 151-153°C
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
Gemcitabine derivative. An antineoplastic agent.

REFERENCES

  • Balzarini, J., et al.: Biochem. Pharmacol., 37, 897 (1988)
  • Abbruzzese, J., et al.: Investig. New Drugs, 7, 195 (1988)
  • Balzarini, J., et al.: J. Biol. Chem., 264, 6127 (1988)
  • Chu, C., et al.: Antimicrob. Agents Chemother., 39, 979 (1988)