Galanthamine N-Oxide

• Catalog No.: G188525
• CAS Number: 134332-50-6
• M. F.: C17H21NO4
• M. W.: 303.35294
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1S,12S,14R)-14-hydroxy-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^1,^1^2.0^6,^1^7]heptadeca-6(17),7,9,15-tetraen-4-ium-4-olate
• IUPAC Traditional name: (1S,12S,14R)-14-hydroxy-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^1,^1^2.0^6,^1^7]heptadeca-6(17),7,9,15-tetraen-4-ium-4-olate
• Synonyms: Galanthamine 10-Oxide; (4aS,6R,8aS,11R)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-Oxide; Galanthamine β-N-oxide; Nivalin-oxide

DATABASE IDS

• CAS Number: 134332-50-6

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 136-139°C
• Solubility: Chloroform
• Solubility: DMSO
• Solubility: Methanol.
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of Galanthamine (G188500), a selective acetylcholinesterase inhibitor.

REFERENCES

• Bickel, U., et al.: Clin. Pharmacol. Ther., 50, 420 (1991)
• Mannens, G., et al.: Drug Metab. Dispos., 30, 553 (1991)
• Zhao, Q., et al.: J. Clin. Pharmacol., 42, 428 (1991)
• Geerts, H., et al.: Brain Res., 1033, 186 (1991)