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Galacto-PUGNAc

Catalog No. G153200 Name Toronto Research Chemicals
CAS Number 1145878-98-3 Website http://www.trc-canada.com
M. F. C15H19N3O7 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
[(2Z,4R,5R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-ylidene]amino N-phenylcarbamate
IUPAC Traditional name
[(2Z,4R,5R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-ylidene]amino N-phenylcarbamate
Synonyms
2-(Acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-galactonimidic Acid δ-Lactone
Gal-PUGNAc

DATABASE IDS

CAS Number 1145878-98-3

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
Galacto-PUGNAc is a highly selective inhibitor for β-hexosaminidases HEXA and HEXB is cell-permeable. Galacto-PUGNAc is able to modulate the activity of HEXA and HEXB in tissue culture, increasing ganglioside GM2 levels in neuroblastoma cells

REFERENCES

  • Stubbs, K.A. et al.: Angew. Chem. Int. Ed., 48, 1300 (2009)