Fusidic Acid-d6

• Catalog No.: F865502
• M. F.: C31H48O6
• M. W.: 516.70922
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 2-[(1S,2S,5R,6S,7S,10S,11S,13R,14Z,15R,17R)-13-(acetyloxy)-5,17-dihydroxy-2,6,10,11-tetramethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-ylidene]-6-(^2H₃)methyl(7,7,7-^2H₃)hept-5-enoic acid
• IUPAC Traditional name: 2-[(1S,2S,5R,6S,7S,10S,11S,13R,14Z,15R,17R)-13-(acetyloxy)-5,17-dihydroxy-2,6,10,11-tetramethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-ylidene]-6-(^2H₃)methyl(7,7,7-^2H₃)hept-5-enoic acid
• Synonyms: NSC 56192-d6; Fucithalmic-d6; (3α,4α,8α,9β,11α,13α,147β,167β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic Acid-d6; Fusidinic Acid-d6; Flucidin-d6; Ramycin-d6; SQ 16603-d6

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 183-186°C
• Solubility: hloroform
• Solubility: methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.

REFERENCES

• Collignon, P., et al.: Int. J. Antimicrob. Agents, 12, S45 (1999)
• Di Marco, R., et al.: J. Autoimmun., 13, 187 (1999)
• Price, C.T., et al.: J. Antimicrob., Chemother., 44, 57 (1999)