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Fostamatinib Disodium Hexahydrate_Molecular_structure_CAS_914295-16-2)
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Fostamatinib Disodium Hexahydrate

Catalog No. F745500 Name Toronto Research Chemicals
CAS Number 914295-16-2 Website http://www.trc-canada.com
M. F. C23H24FN6Na2O9P Telephone +1 (416) 665-9696
M. W. 624.4231642 Fax +1 (416) 665-4439
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SYNONYMS

IUPAC name
disodium [6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-4-yl]methyl phosphate
IUPAC Traditional name
disodium [6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl phosphate
Synonyms
6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one Sodium Salt Hydrate

DATABASE IDS

CAS Number 914295-16-2

PROPERTIES

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DETAILS

Description (English)
A spleen tyrosine kinase inhibitor prodrug for the treatment of inflammatory diseases. An anti-inflammatory agent.

REFERENCES

  • Weinblatt, M., et al.: Arthritis Rheum., 48, 35 (2003)
  • Cha, H., et al.: J. Pharmacol. Exp. Ther., 317, 571 (2003)