Forskolin

• Catalog No.: F701800
• CAS Number: 66575-29-9
• M. F.: C22H34O7
• M. W.: 410.50116
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
• IUPAC Traditional name: forskolin
• Synonyms: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-Naphtho[2,1-b]pyran-1-one; (-)-Forskolin; HL 362; L 75-1362B; Colforsin; ForsLean; NSC 357088; Coleonol

DATABASE IDS

• CAS Number: 66575-29-9

PROPERTIES

• Apperance: White Solid
• Melting Point: 219-222°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.

REFERENCES

• Lindner, E., et al.: Arzneim.-Forsch., 28, 284 (1984)
• Hoever, G., et al.: J. Med. Chem., 48, 1256 (1984)
• Lai, S., et al.: Eur. J. Clin. Microbiol. Infect. Dis., 24, 5831 (1984)