Fluticasone-d5 Furoate

• Catalog No.: F599512
• M. F.: C27H29F3O6S
• M. W.: 538.5757696

SYNONYMS

• IUPAC name: (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14-({[fluoro(^2H₂)methyl]sulfanyl}carbonyl)-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl (^2H₃)furan-2-carboxylate
• IUPAC Traditional name: (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14-({[fluoro(^2H₂)methyl]sulfanyl}carbonyl)-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl (^2H₃)furan-2-carboxylate
• Synonyms: (6α,11β,16α,17α)-6,9-Difluoro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carbothioic Acid S-(Fluoromethyl) Ester-d5; Avamys-d5; Allermist-d5; GSK 685 698-d5; GW 685698X-d5

DETAILS

Description (English)

Labelled Fluticasone Furoate (F599510). A synthetic corticosteroid derived from fluticasone for treatment of seasonal allergic rhinitis.

REFERENCES

• DeWester, J., et al.: Allergy Asthma Proc., 24, 331 (2003)
• Hughes, S., et al.: Drug Metab. Dispos., 36, 2337 (2003)
• Meltzer, E., et al.: Clin. Drug Investig., 29, 79 (2003)