Fluticasone Propionate-d3

• Catalog No.: F599505
• M. F.: C25H31F3O5S
• M. W.: 500.5708496
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14-{[(fluoromethyl)sulfanyl]carbonyl}-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl (3,3,3-^2H₃)propanoate
• IUPAC Traditional name: (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14-{[(fluoromethyl)sulfanyl]carbonyl}-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl (3,3,3-^2H₃)propanoate
• Synonyms: CCI 18781-d3; Atemur Mite-d3; Cutivate-d3; Flonase-d3; Flovent-d3; (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid-d3 S-(Fluoromethyl) Ester; Flixonase-d3; Flutide-d3; Flutide N-d3; Flutivate-d3; Zofluf-d3

PROPERTIES

• Apperance: White Solid
• Melting Point: >190°C (dec.)
• Solubility: Chloroform
• Solubility: DMSO
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A labelled derivative of Flumethasone. An antiallergic; anti-asthmatic; anti-inflammatory.

REFERENCES

• Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990)
• Mitchison, H.C., et al.: Gut, 32, 260 (1990)
• Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)