6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one

• Catalog No.: F596600
• CAS Number: 841290-80-0
• M. F.: C22H23FN6O5
• M. W.: 470.4536232

SYNONYMS

• IUPAC name: 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one
• IUPAC Traditional name: 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
• Synonyms: 6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenylamino]pyrimidin-4-ylamino]-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

DATABASE IDS

• CAS Number: 841290-80-0

DETAILS

Description (English)

Intermediate used for preparation of prodrugs of pyrimidine-2,4-diamines as anticancer agents.

REFERENCES

• Atwell, S., et al.: J. Biol. Chem., 279, 55827 (2004)
• Braselmann, S., et al.: J. Pharmacol. Exp. Ther., 319, 998 (2004)
• Hirabayashi, A., et al.: Bioorg. Med. Chem., 16, 7347 (2004)