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(E)-3-(2-Fluorophenyl)-N-((S)-1-(3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]acrylamide_Molecular_structure_CAS_697287-48-2)
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(E)-3-(2-Fluorophenyl)-N-((S)-1-(3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]acrylamide

Catalog No. F595708 Name Toronto Research Chemicals
CAS Number 697287-48-2 Website http://www.trc-canada.com
M. F. C19H19FN2O2 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
(2E)-N-[(1S)-1-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)ethyl]-3-(2-fluorophenyl)prop-2-enamide
IUPAC Traditional name
(2E)-N-[(1S)-1-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)ethyl]-3-(2-fluorophenyl)prop-2-enamide
Synonyms
N-[(1S)-1-(3,4-Dihydro-2H-1,4-benzoxazin-6-yl)ethyl]-3-(2-fluorophenyl)-2-propenamide

DATABASE IDS

CAS Number 697287-48-2

PROPERTIES

Certificate of Analysis Download
Apperance Light-Yellow Foam
Solubility Dichloromethane
Solubility Methanol
MSDS Link Download

DETAILS

Description (English)
A potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability.

REFERENCES

  • Yokoo, H., et al.: Br. J. Pharmacol., 131, 779 (2000)
  • Wu, Y-J., et al.: Bioorg. Med. Chem. Lett., 14, 1991 (2000)