4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride_Molecular_structure_CAS_1012886-75-7)

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4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride
Catalog No.	F595220	Name	Toronto Research Chemicals
CAS Number	1012886-75-7	Website	http://www.trc-canada.com
M. F.	C12H15ClFN	Telephone	+1 (416) 665-9696
M. W.	227.7056032	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage	-20°C Freezer, Under Inert Atmosphere	Chembase ID: 169174

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SYNONYMS

IUPAC name

4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine hydrochloride

IUPAC Traditional name

4-(4-fluorophenyl)-1-methyl-3,6-dihydro-2H-pyridine hydrochloride

Synonyms

4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine Hydrochloride

1-Methyl-4-(4'-fluorophenyl)-1,2,3,6-tetrahydropyridine Hydrochloride

DATABASE IDS

CAS Number

1012886-75-7

PROPERTIES

Certificate of Analysis	Download
Apperance	Off-White Solid
Melting Point	171-174°C
Solubility	Methanol
Solubility	Water
MSDS Link	Download
Storage Condition	-20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

The active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (M325910), N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease.

REFERENCES

Gerlach, M., et al.: Eur. J. Pharmacol., 208, 273 (1991)
Tipton, K., et al.: J. Neurochem., 61, 1191 (1991)
Wimalasena, D., et al.: J. Biol. Chem., 279, 15298 (1991)