4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide_Molecular_structure_CAS_125971-96-2)

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4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide
Catalog No.	F593700	Name	Toronto Research Chemicals
CAS Number	125971-96-2	Website	http://www.trc-canada.com
M. F.	C26H24FNO3	Telephone	+1 (416) 665-9696
M. W.	417.4720632	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage	-20°C Freezer	Chembase ID: 67287

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SYNONYMS

IUPAC name

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide

IUPAC Traditional name

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide

Synonyms

2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic Acid Phenylamide

DATABASE IDS

CAS Number

125971-96-2

PROPERTIES

Certificate of Analysis	Download
Apperance	White Solid
Melting Point	196-198°C
Solubility	Chloroform
MSDS Link	Download
Storage Condition	-20°C Freezer

DETAILS

Description (English)

An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

REFERENCES

Winters, R., et al.: J. Med. Chem., 36, 1735 (1993)
Hagmann, W., et al.: Bioorg. Med. Chem. Lett., 10, 1975 (1993)
Istvan, E., et al.: Science, 292, 1160 (2001)