9-Fluoro-16α,17-(isopropylidenedioxy) Corticosterone

• Catalog No.: F592050
• CAS Number: 1524-86-3
• M. F.: C24H33FO6
• M. W.: 436.5136232
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icos-17-en-16-one
• IUPAC Traditional name: (1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icos-17-en-16-one
• Synonyms: (11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione; 11β,16α,17α,21-Tetrahydroxy-9α-fluoropregn-4-ene-3,20-dione 16,17-Acetonide; 9-fluoro-11β,16α,17,21-Tetrahydroxypregn-4-ene-3,20-dione cyclic 16,17-Acetal with Acetone; NSC 21915

DATABASE IDS

• CAS Number: 1524-86-3

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: 249-254°C (dec.)
• Solubility: Chloroform
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Synthetic fluorinated corticosteroid tested for inhibition of granuloma in rats and for vasoconstriction activity in human subjects; potential topical antiinflammatory agent.

REFERENCES

• Hannah, J. et al.: J. Med. Chem., 18, 168 (1975)