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N-[4-[1-(2-Fluorobenzyl)-3-butyl-2,6-dixo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]phenyl]acetamide_Molecular_structure_CAS_628279-07-2)
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N-[4-[1-(2-Fluorobenzyl)-3-butyl-2,6-dixo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]phenyl]acetamide

Catalog No. F588520 Name Toronto Research Chemicals
CAS Number 628279-07-2 Website http://www.trc-canada.com
M. F. C25H26FN5O3 Telephone +1 (416) 665-9696
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SYNONYMS

IUPAC name
N-[4-({3-butyl-1-[(2-fluorophenyl)methyl]-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl}methyl)phenyl]acetamide
IUPAC Traditional name
N-[4-({3-butyl-1-[(2-fluorophenyl)methyl]-2,6-dioxo-7H-purin-8-yl}methyl)phenyl]acetamide
Synonyms
N-[4-[[3-Butyl-1-[(2-fluorophenyl)methyl]-2,3,6,9-tetrahydro-2,6-dioxo-1H-purin-8-yl]methyl]phenyl]acetamide

DATABASE IDS

CAS Number 628279-07-2

PROPERTIES

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DETAILS

Description (English)
It is used for the preparation of amide-substituted xanthine derivatives as phosphoenolpyruvate carboxykinase inhibitors with gluconeogenesis modulating activity for treating type 2 diabetes.

REFERENCES

  • Kawashima, Y., et al.: Chem. Pharm. Bull., 43, 1132 (1995)
  • Sun, Y., et al.: J. Biol. Chem., 277, 23301 (1995)
  • Foley, L., et al.: Bioorg. Med. Chem. Lett., 13, 3871 (1995)