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Fluocortolone

Catalog No. F500500 Name Toronto Research Chemicals
CAS Number 152-97-6 Website http://www.trc-canada.com
M. F. C22H29FO4 Telephone +1 (416) 665-9696
M. W. 376.4616632 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 169061

SYNONYMS

IUPAC name
(1S,2R,8S,10S,11S,13R,14S,15S,17S)-8-fluoro-17-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
IUPAC Traditional name
fluocortolone
Synonyms
6α-Fluoro-16α-methyl-Δ1-corticosterone
16α-Methyl-6α-fluoro-Δ1,4-pregnadien-11β,21-diol-3,20-dione
Flucortolone
Fluocortolon
(6α,11β,16α)-6-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
SH 742

DATABASE IDS

CAS Number 152-97-6

PROPERTIES

Certificate of Analysis Download
Apperance Pale Yellow Solid
Melting Point 113-116°C
Solubility Chloroform
Solubility Dioxane
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids. Fluocortolone is similar to Fluocortin, but with one less keto group.

REFERENCES

  • Breuer, et al.: Arzneim.-Forsch., 15, 50 (1965)
  • Domenico, et al.: Arzneim.-Forsch., 15, 46 (1965)
  • Gerhards, et al.: Acta Endocrinol., 68, 98 (1965)