Fluasterone

• Catalog No.: F500300
• CAS Number: 112859-71-9
• M. F.: C19H27FO
• M. W.: 290.4154832

SYNONYMS

• IUPAC name: (1S,2R,10R,11S,13R,15S)-13-fluoro-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-7-en-14-one
• IUPAC Traditional name: (1S,2R,10R,11S,13R,15S)-13-fluoro-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-7-en-14-one
• Synonyms: (16α)-Fluoro-5-androsten-17-one

DATABASE IDS

• CAS Number: 112859-71-9

DETAILS

Description (English)

A synthetic derivative of Dehydroepiandrosterone. The reduced androgenicity of Fluasterone may obviate toxicities associated with the androgenicity of the parent compound. Antitumor agent. Used in clinical trials for prostate cancer prevention.

REFERENCES

• Bentley, P., et al.: Food Chem. Toxicol., 31, 857 (1993)
• Rao, K., et al.: Cancer Res., 59, 3084 (1993)
• Masuzaki, H., et al.: Science, 294, 2166 (1993)
• Osawa, E., et al.: Life Sci., 70, 2623 (1993)