Flucloronide

• Catalog No.: F418900
• CAS Number: 3693-39-8
• M. F.: C24H29Cl2FO5
• M. W.: 487.3884632

SYNONYMS

• IUPAC name: (1S,2S,4R,8S,9S,11S,12R,13S,19S)-11,12-dichloro-19-fluoro-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^2,^9.0^4,^8.0^1^3,^1^8]icosa-14,17-dien-16-one
• IUPAC Traditional name: flucloronide
• Synonyms: Topilar; 9,11β-Dichloro-6α-fluoro-21-hydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione; 9α,11β-Dichloro-6α-fluoro-16α,17α,21-trihydroxypregna-1,4-diene-3,20-dione-16,17-acetonide; Flucortolone acetonide; Fluclorolone acetonide; (6α,11β,16α)-9,11-Dichloro-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione; RS 2252

DATABASE IDS

• CAS Number: 3693-39-8

DETAILS

Description (English)

A synthetic glucocorticoid with anti-inflammatory properties. Studies suggest that it is a potent inhibitor of mouse skin tumor promotion and epidermal DNA synthesis.

REFERENCES

• Malone, T. et al.: Br. J. Dermatol., 90, 187 (1974)
• Dorfman, R.I. et al.: Acta Endorcinol., 49, 262 (1974)
• Schwarz, J.A. et al.: Chem.-Biol. Inter., 17, 331 (1974)