(E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity

• Catalog No.: F370020
• CAS Number: 131944-48-4
• M. F.: C44H69NO12
• M. W.: 804.01816
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1R,9S,12R,13E,15S,16S,19R,20E,23S,25S,26R,27R,29R)-1,16-dihydroxy-12-[(1R,3S,4R)-4-hydroxy-3-methoxycyclohexyl]-25,27-dimethoxy-13,15,21,23,29-pentamethyl-19-(prop-2-en-1-yl)-11,30-dioxa-4-azatricyclo[24.3.1.0^4,^9]triaconta-13,20-diene-2,3,10,18-tetrone
• IUPAC Traditional name: (1R,9S,12R,13E,15S,16S,19R,20E,23S,25S,26R,27R,29R)-1,16-dihydroxy-12-[(1R,3S,4R)-4-hydroxy-3-methoxycyclohexyl]-25,27-dimethoxy-13,15,21,23,29-pentamethyl-19-(prop-2-en-1-yl)-11,30-dioxa-4-azatricyclo[24.3.1.0^4,^9]triaconta-13,20-diene-2,3,10,18-tetrone
• Synonyms: [3R-[3R*(1R*,3R*,4R*),4E,6S*,7S*,10R*,11E,14S*,16S*,17R*,18S*,20R*,21R*,28aS*]]-7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-Hexadecahydro-7,21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-10-(2-propenyl)-7,21-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclopentacosine-1,9,22,23(6H,25H)-tetrone

DATABASE IDS

• CAS Number: 131944-48-4

PROPERTIES

• Apperance: White to Pale Yellow Solid
• Melting Point: 115-120°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

FK-506 (F370000) impurity. A new macrolite of thermal rearrangement of the immunosuppressant FK-506.

REFERENCES

• Ok, H., et al.: Tetrahedron Lett., et al.: 31, 6477 (1990)