Finasteride-d9

• Catalog No.: F342002
• M. F.: C23H36N2O2
• M. W.: 372.54414
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2R,7R,10S,11S,14S,15S)-2,15-dimethyl-N-[2-(^2H₃)methyl(^2H₆)propan-2-yl]-5-oxo-6-azatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-3-ene-14-carboxamide
• IUPAC Traditional name: (1S,2R,7R,10S,11S,14S,15S)-2,15-dimethyl-N-[2-(^2H₃)methyl(^2H₆)propan-2-yl]-5-oxo-6-azatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-3-ene-14-carboxamide
• Synonyms: Prostide-d9; (5α,17β)-N-(1,1-Dimethylethyl-d9)-3-oxo-4-azaandrost-1-ene-17-carboxamide; Proscar-d9; MK-906-d9; Finastid-d9

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 252-254°C (dec.)
• Solubility: Chloroform
• Solubility: DMSO
• Solubility: Methanol
• Solubility: n-Propanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

The labelled version of Finasteride. An inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. Antialopecia agent.

REFERENCES

• Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993)
• Tenover, J.L., et al.: Clin. Ther., 19, 243 (1993)
• McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1993)