Fialuridine-15N2,13C

• Catalog No.: F335002
• M. F.: C9H10FIN2O5
• M. W.: 375.06844583

SYNONYMS

• IUPAC name: 1-[(2R,3R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydro(2-^1^3C,1,3-^1^5N₂)pyrimidine-2,4-dione
• IUPAC Traditional name: 1-[(2R,3R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo(2-^1^3C,1,3-^1^5N₂)-3H-pyrimidine-2,4-dione
• Synonyms: 1-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl) -5-iodouracil-15N2,13C; FIAU-15N2,13C; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodo-2,4(1H,3H-pyrimi- dinedione-15N2,13C; 5-Iodo-2'-fluoroarauracil-15N2,13C

DETAILS

Description (English)

An antiviral agent; nucleoside analog with antihepatitis B activity.

REFERENCES

• Watanabe A., et al.: J. Med. Chem., 22, 21 (1979)
• Colacino, J.M., et al.: Antimicrob. Agents Chemother., 24, 505 (1979)
• Staschke, K.A., et al.: Antiviral Res., 23, 45 (1979)
• Cui, L., et al.: J. Clin. Invest., 95, 555 (1979)