Falecalcitriol

• Catalog No.: F101110
• CAS Number: 83805-11-2
• M. F.: C27H38F6O3
• M. W.: 524.5792392

SYNONYMS

• IUPAC name: (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-7,7,7-trifluoro-6-hydroxy-6-(trifluoromethyl)heptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• IUPAC Traditional name: hornel
• Synonyms: (1R,4S,5Z)-4-Methylene-5-[(2E)-2-[1-[(1R)-6,6,6-trifluoro-5-hydroxy-1-methyl-5-(trifluoromethyl)hexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol; F6-1α,25-Dihydroxyvitamin D3; Flocalcitriol; Hornel; Fulstan; 26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitamin D3; Flocacitriol; (1α,3β,5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol; Ro 23-4194; ST 630; (+)-(5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1α,3β,25-triol

DATABASE IDS

• CAS Number: 83805-11-2

DETAILS

Description (English)

Hexafluorinated analog of Calcitriol (C144500). A more potent therapeutic agent for secondary hyperparathyroidism.

REFERENCES

• Imanishi, Y. et al.: J. Steroid Biochem. Mol. Biol., 70, 243 (1999)
• Morii, H. et al.: Clin. Calc., 15, 29 (1999)
• Brown, A.J. et al.: Treat. Endocrinol., 1, 313 (1999)