Ezetimibe Hydroxy-d4 β-D-Glucuronide

• Catalog No.: E975037
• M. F.: C30H29F2NO9
• M. W.: 585.5493664

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6R)-6-[(1S)-3-[(2S,3R)-1-[4-fluoro(^2H₄)phenyl]-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]-1-(4-fluorophenyl)propoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6R)-6-[(1S)-3-[(2S,3R)-1-[4-fluoro(^2H₄)phenyl]-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl]-1-(4-fluorophenyl)propoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: SCH 488128-d4; (1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl-d4)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl β-D-Glucopyranosiduronic Acid

DETAILS

Description (English)

A labelled metabolite of Ezetimibe. Antilipemic.

REFERENCES

• Shah, V., et al.: J. Pharm. Sci., 17, 1551 (2000)
• Van Heek, M., et al.: Br. J. Pharmacol., 134, 409 (2000)
• Patrick, J., et al.: Drug Metab. Dispos., 30, 430 (2000)