Ezetimibe-d4 β-D-Glucuronide, >85%

• Catalog No.: E975032
• M. F.: C30H29F2NO9
• M. W.: 585.5493664
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-1-[4-fluoro(^2H₄)phenyl]-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-1-[4-fluoro(^2H₄)phenyl]-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: Sch 58235-d4 Glucuronide; Sch 60663-d4; Ezetimibe-d4 Phenoxy Glucuronide; 4-[(2S,3R)-1-(4-Fluorophenyl-d4)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid

PROPERTIES

• Apperance: White Solid
• Melting Point: 140-150°C
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Phase-II labelled metabolite of Ezetimibe, an antihyperlipoproteinemic. A cholesterol absorption inhibitor.

REFERENCES

• van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997)
• van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)