Ezetimibe Phenoxy β-D-Glucuronide

• Catalog No.: E975030
• CAS Number: 190448-57-8
• M. F.: C30H29F2NO9
• M. W.: 585.5493664
• Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: EZM-G; Sch 58235 Glucuronide; 4-[(2S,3R)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid; Ezetimibe Phenoxy Glucuronide; Sch 60663

DATABASE IDS

• CAS Number: 190448-57-8

PROPERTIES

• Apperance: White Solid
• Melting Point: 140-150°C
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under inert atmosphere

DETAILS

Description (English)

Phase-II metabolite of Ezetimibe, an antihyperlipoproteinemic. A Cholesterol absorption inhibitor.This compound is very hygroscopic. Handle with care.

REFERENCES

• van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997)
• van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)