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5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione(Pioglitazone Impurity)_Molecular_structure_CAS_144809-28-9)
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5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione(Pioglitazone Impurity)

Catalog No. E925590 Name Toronto Research Chemicals
CAS Number 144809-28-9 Website http://www.trc-canada.com
M. F. C19H18N2O3S Telephone +1 (416) 665-9696
M. W. 354.42282 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 168740

SYNONYMS

IUPAC name
(5Z)-5-({4-[2-(5-ethylpyridin-2-yl)(2H4)ethoxy]phenyl}methylidene)-1,3-thiazolidine-2,4-dione
IUPAC Traditional name
(5Z)-5-({4-[2-(5-ethylpyridin-2-yl)(2H4)ethoxy]phenyl}methylidene)-1,3-thiazolidine-2,4-dione
Synonyms
Didehydropioglitazone
5-[4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzylidene]thiazolidine-2,4-dione

DATABASE IDS

CAS Number 144809-28-9

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 156-159°C
Solubility Dimethylformamide
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
A novel intermediate of Pioglitazone (P471000).

REFERENCES

  • Diaz, J., et al.: J. Biol. Chem., 272, 11350 (1997)
  • Day, C., et al.: Diabet Med., 16, 179 (1997)
  • Motomura, W., et al.: Cancer Res., 60, 5558 (1997)
  • Koeffler, H., et al.: Clin. Cancer Res., 9, 1 (1997)