Etoposide 3',4'-Quinone

• Catalog No.: E933760
• CAS Number: 105016-65-7
• M. F.: C28H28O13
• M. W.: 572.51412

SYNONYMS

• IUPAC name: 5-[(10R,11R)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-12-oxo-4,6,13-trioxatetracyclo[7.7.0.0^3,^7.0^1^1,^1^5]hexadeca-1(9),2,7-trien-10-yl]-3-methoxycyclohexa-3,5-diene-1,2-dione
• IUPAC Traditional name: 5-[(10R,11R)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-12-oxo-4,6,13-trioxatetracyclo[7.7.0.0^3,^7.0^1^1,^1^5]hexadeca-1(9),2,7-trien-10-yl]-3-methoxycyclohexa-3,5-diene-1,2-dione
• Synonyms: 5-[(5R,5aR,8aR,9S)-9-[(4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl)oxy]-5,5a,6,8,8a,9-hexahydro-6-oxofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-5-yl]-3-methoxy-3,5-cyclohexadiene-1,2-dione; Etoposide o-Quinone

DATABASE IDS

• CAS Number: 105016-65-7

PROPERTIES

• Apperance: Dark Brown Solid
• Solubility: Chloroform
• Solubility: Dichloromethane

DETAILS

Description (English)

Precursor to the semiquinone free radical of Etoposide, believed to inactivate φX174 DNA.

REFERENCES

• Kagan, V., et al.: Biochem., 33, 9651 (1994)
• Gantchev, T., et al.: Mol. Pharmacol., 53, 422 (1994)
• Fan, Y., et al.: Chem. Res. Toxicol., 20, 1067 (1994)
• Alegria, A., et al.: Free Rad. Res., 42, 70 (1994)