Etoposide-d3

• Catalog No.: E933752
• M. F.: C29H32O13
• M. W.: 588.55658
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-[4-hydroxy-3-(^2H₃)methoxy-5-methoxyphenyl]-4,6,13-trioxatetracyclo[7.7.0.0^3,^7.0^1^1,^1^5]hexadeca-1(9),2,7-trien-12-one
• IUPAC Traditional name: (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-[4-hydroxy-3-(^2H₃)methoxy-5-methoxyphenyl]-4,6,13-trioxatetracyclo[7.7.0.0^3,^7.0^1^1,^1^5]hexadeca-1(9),2,7-trien-12-one
• Synonyms: VePesid-d3; EPEG; Zuyeyidal-d3; (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one-d3; -d3 P 16-213-d3; Vepesid J-d3; trans-Etoposide-d3

PROPERTIES

• Storage Condition: -20°C Freezer, Under Inert Atmosphere
• Apperance: Off-White Solid
• Melting Point: >170°C (dec.)
• Solubility: Acetonitrile
• Solubility: Chloroform
• Solubility: Methanol

DETAILS

Description (English)

A labelled DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic.

REFERENCES

• Burden, D.A., et al.: J. Biol. Chem., 271, 29238 (1996)
• Joel, S., et al.: Cancer Treat. Rev., 22, 179 (1996)