Etoposide

• Catalog No.: E933750
• CAS Number: 33419-42-0
• M. F.: C29H32O13
• M. W.: 588.55658
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^3,^7.0^1^1,^1^5]hexadeca-1(9),2,7-trien-12-one
• IUPAC Traditional name: etoposide
• Synonyms: Vepesid; (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; trans-Etoposide; Zuyeyidal; Vepesid J; EPEG; P 16-213

DATABASE IDS

• CAS Number: 33419-42-0

PROPERTIES

• Apperance: White Solid
• Melting Point: 254-256°C
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic.

REFERENCES

• Burden, D.A., et al.: J. Biol. Chem., 271, 29238 (1996)
• Joel, S., et al.: Cancer Treat. Rev., 22, 179 (1996)