(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

• Catalog No.: E917350
• CAS Number: 110351-94-5
• M. F.: C13H13NO5
• M. W.: 263.24602

SYNONYMS

• IUPAC name: (4S)-4-ethyl-4-hydroxy-1H,3H,4H,6H,7H,8H,10H-pyrano[3,4-f]indolizine-3,6,10-trione
• IUPAC Traditional name: (4S)-4-ethyl-4-hydroxy-1H,7H,8H-pyrano[3,4-f]indolizine-3,6,10-trione
• Synonyms: (S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

DATABASE IDS

• CAS Number: 110351-94-5

DETAILS

Description (English)

(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is a key intermediate in the synthesis of Irinotecan (I767500) and Camptothecin (C175150) analogs.

REFERENCES

• Hsiang, Y., et al.: J. Biol. Chem., 260, 14873 (1985)
• Bao, Y., et al.: Chin. J. Med. Chem., 18, 263 (1985)
• Miao, Z., et al.: Bioorg. Med. Chem., 16, 1493 (1985)