(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione-d5

• Catalog No.: E917302
• M. F.: C13H13NO5
• M. W.: 263.24602
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (4S)-4-(^2H₅)ethyl-4-hydroxy-1H,3H,4H,6H,7H,8H,10H-pyrano[3,4-f]indolizine-3,6,10-trione
• IUPAC Traditional name: (4S)-4-(^2H₅)ethyl-4-hydroxy-1H,7H,8H-pyrano[3,4-f]indolizine-3,6,10-trione
• Synonyms: (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione-d5; (S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione-d5

PROPERTIES

• Apperance: Dark Yellow Solid
• Solubility: Dichloromethane
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Used in the preparation of Camptothecin derivatives, for their therapeutic use as antitumor agents.

REFERENCES

• Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986)
• Miller, K.D., et al.: Invest. New Drugs, 22, 69 (1986)
• Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (1986)
• Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (1986)